![]() ![]() Įctopic manifestations beyond the hand can be seen in Plantar fibromatosis - see Plantar fibromatosis (plantar fascia), 10% to 30% Peyronie disease (Dartos fascia of the penis), 2% to 8% and Garrod disease (dorsal knuckle pads), 40% to 50%. It is associated with diabetes, seizure disorders, smoking, alcoholism, HIV, and vascular disease. Image 1: Clinical presentation of Dupuytren contracture Etiology ĭupuytren disease is a genetic disorder expressed in an autosomal dominant fashion, but most frequently seen with a multifactorial etiology. In many individuals, there is a family history with males being more susceptible to the condition than females.When unilateral, the right side is more likely to be involved compared to the left. Dupuytren contracture is usually seen in Caucasians and the disorder often presents bilaterally.The nodules form cords that produce contracture deformities within fascial bands and tissues of the hand. ![]() The disease begins in the palm as painless nodules that form along longitudinal lines of tension.the fourth (ring) and fifth (pinky) digits. Commonly affected digits are those farthest from the thumb i.e. ![]()
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